Program for the Human Environment

Together with colleagues at Mt. Sinai School of Medicine, we report a new mathematical approach to the genetic structure of biodiversity, using indicator vectors calculated from short DNA sequences. Sirovich L, Stoeckle MY, Zhang Y (2009) A Scalable Method for Analysis and Display of DNA Sequences. PLoS ONE 4(10): e7051. This method is scalable to the largest datasets envisioned in this field and provides a macroscopic view of “biodiversity space”. It offers a complement to tree-building techniques and could enable automated classification at various taxonomic levels.  

Zip files containing MatLab code and datasets utilized in paper can be downloaded from here.